A quick note on ESPR as I somehow missed the FDA news this morning that a couple of you kindly pointed out. This makes the move much more reasonable than I first thought. So what does this mean? First, the odds of the drugs approval are likely higher given the LDL lowering endpoint is easier […]
March 20 Biotech Update
Another week and another attempt at the 300 level on the IBB and another week with no real M&A. We are still dealing with the aftermath of the AMGN data and while there seems to be some recovery, I want to spend today talking about a potential implication that seems to have been flying under […]
March 17 Biotech Update
Well, this is not going to be a good day for the sector and that wall at 300 in the IBB is likely safe for now. The key culprit is going to be the AMGN outcomes data, which is a massive disappointment (for anyone outside of AMGN who apparently think it is great). While one […]
March 14 Biotech Update
The sector is on the edge of either breaking down or breaking out. While it is hard to have very strong conviction, I would lean towards a breakout especially given the potential news this week. Obviously the data can change where we move but I do think it will send a sign as to the […]
March 13 Biotech Update
Certainly getting some more news and events that could be driving the sector but nothing really thesis changing, we need to wait for the end of the week with the PCSK9 data. As we wait for that data, there are some interesting notes and company specific information that we can talk about. 1. KPTI was […]
March 10 Biotech Update
The sector has been interesting. Given the past 18 months, it feels easy to be bearish on every pullback consolidation but I am incrementally more positive. It is starting to feel more like a pause at an important level of resistance as opposed to the start of a large retracement. Obviously we likely need some […]
March 8 Biotech Update
I was not too busy to write yesterday but there was really nothing that I could find that was interesting enough to write about. I looked for something and there was a big lack of company specific news and that is the case today as well. We are a little too early to talk about […]
March 6 Biotech Update
There is a little bit of news to start the week but nothing that likely seems thesis changing or will have a dramatic impact on sentiment/trends. We are in the tail end of earnings with a drum beat of small caps that might have some impact on the individuals companies but little on the sector. […]
March 3 Biotech Update
I think the sector has been rational the past couple of days in that good news is generally moving stocks higher and bad news lower. If there was a broader trend I would say weak but it almost seems out of sync with the broader market. When the broader market rallied the sector lagged and […]
March 1 Biotech Update
Not a lot of news the past couple of days but certainly some interesting events to talk about. I will focus on two but more generally the sector is doing well. There seems to be some more interest in the sector and the move in CELG might be that early warning signal of generalist interest […]
February 27 Biotech Update
I have snuck into work during this Mardi Gras break but not much to write on so this will be a quick update and will likely be back later in the week. 1. ONCS held up better than I thought it would and with the fast track news today and KOL talk tomorrow, I will […]
February 24 Biotech Update
Weakness (sort of) continuing in the sector but perhaps that is simply drifting or consolidation after its recent performance. In either case, it still seems like people are unwilling to fully commit to the sector and my early warning signal of generalist entrance (and likely sustained outperformance) will be outperformance of CELG. That is a […]
February 22 Biotech Update
A little bit of news since yesterday and I will focus on them but more broadly the sector seemed to struggle yesterday. It had been outperforming so a day of relative weakness is not unexpected but was certainly a sell biotech and buy everything else sort of day. Let us see if that pattern continues […]
February 21 Biotech Update
Long weekend and a significant lack of news. I do not think there was an expectation of big news but sometimes these long weekends can surprise with a flurry of mergers- not today. Without anything major I will do a series of quick hits on the news since last Friday. Market is doing well to […]
February 17 Biotech Update
Some news to talk about today in a couple stocks and one idea I want to float that has been ruminating in my mind. The sector continues to do well as is the market in general. There has been some talk that the melt up is related to a massive synthetic short position in the […]
February 15 Biotech Update
We have some additional news yesterday but nothing that is necessarily positive for the sector. It certainly rallied in the afternoon and I suspect there is enough juice left for that to continue. Of course, we are only one tweet away from a pullback but I guess that is true of every sector and stock. […]
February 14 Biotech Update
Some decent news this morning for the sector but not quite a robust reaction. Perhaps the sector needs to pause after its recent run or perhaps it will rally later but I would have expected a little more follow through. It is still early and regardless of the price action the sector needs to continue […]
February 13 Biotech Update
A relatively slow start to the week, so I will start off with perhaps the most (maybe only) meaningful fundamental news and then highlight another stock that is very likely under the radar. We have a couple of investor conferences which tend to focus on small caps, so there could be some pick up in […]
February 10 Biotech Update
So I think we need to be prepared for some more backlash and bad press given the decision by Marathon to think it is business as usual. So far the backlash has been isolated but it is difficult to see this not become a political talking point. 1. Marathon licensed an old, generic steroid (DFZ) […]
February 8 Biotech Update
Certainly some news for the sector and not great news but it seems to be having limited impact on the broader sector. In other words, people seem to be seeing GILD problems as isolated to GILD and not the broader sector but that is certainly something we need to watch. 1. I am very glad […]














