May 30- EOD

A bit of a quite day today in the markets. There is some biotech news but it seems to be the calm before the storm of ASCO, or as I heard someone note- the fire hose of data. 1. At the ELN annual meeting someone asked them about the possibility of purchasing AMRN and they […]

May 29- EOD

It seemed like a nice selloff in biotech today. There were the occasional winners (INFI) but for the most part it was a sea of red today. The summer months can be difficult times for biotechs but they have been quite resilient and these sell-offs have ended up being good buying opportunities. 1. I want […]

May 28- Mid Day

This is mid-day instead of the end of the day because I will be out of the office for the rest of the afternoon. This is a little shorter than it should be given the news and moves today but I should have time to add more to this tomorrow. 1. Looks like I have […]

Week’s Option Activity (5/20~5/24)

The following stocks had notable activity in their options during the past week: $JAZZ (5/20): 4,000 SEP/JUN 55.0 strike Put Time spreads were traded (stock @ $58.36) for a net debit of 3.15 or $1,260,000. Specifically, 4,000 JUN 55.0 strike Puts were sold for 1.15 against a purchase of 4,000 SEP 55.0 strike Puts for […]

May 24 – End Of Day Biotech Wrap-up

Really another slow day entering into the long weekend. From my perspective, there were really only two really interesting moves. 1. AVEO was a bit of a shocker. AVEO disclosed in a filing that Astellas will no longer fund tivozanib in RCC and would not seek approval in the EU. There are still some other […]

May 23 – End Of Day Biotech Wrap-up

Today was another macro day in that the macro environment had a lot more to do with price movements than fundamentals. That being said, bios seemed to be strong in the morning despite the sell-off and move higher when the market reversed. There was not really a lot of new news today but, as always, […]

May 22 – End Of Day Biotech Wrap-up

While the market got some intraday whipsaw action, it seemed generally good and biotechs did well- early. We had a late day sell-off with biotechs seeming to do better than the market in general. 1. It seems like just yesterday I was positive but cautious on ARIA because it was still making lower high and […]

May 21 – End Of Day Biotech Wrap-up

Perhaps it is the start of the summer season but the market seems to have been quite the past couple of days or perhaps I am simply looking at the wrong parts of the market. 1. There were a number of EHA abstracts released today for PCYC and perhaps one of the most important was […]

May 20th – End Of Day Biotech Wrap-up

Outside of a not completely unexpected merger, it was a relatively quite start to the week. As has been par for the course, ASCO oncology stocks tended to be weak but not in a significant manner. Perhaps we are having the quite before the storm. 1. PPHM announced its agreement with the FDA on a […]

Week’s Option Activity (5/13~5/17)

The following stocks had notable activity in their options during the past week: $OPTR (5/13): 2,250 SEP 17.50 strike Calls were sold against equal number of purchased JUN 12.5 Puts (stock @ $12.81) for total debit of 0.85 or $191,250. Trade most likely a hedge of an existing long stock position. $MNTA (5/13): 926 JAN14 […]

Week’s Option Activity (5/6~5/10)

The following stocks had notable activity in their options during the past week: $HOLX (5/7/13): 3,900 DEC 22.0/18.0 strike Strangles were purchased for a net debit of 2.05 or a total cost of $799,500. DEC 22.0 Calls were bought for 1.00 and DEC 18.0 strike Puts were bought for 1.05 (stock at $20.66). Buyer makes […]

ASCO2013 Take Three: PD1 antibodies will have significant presence

This is our third piece in a series of articles on developments expected at ASCO 2013[1,2]. Currently, we think the majority of the exciting presentations at ASCO 2013 will be from clinical candidates at big pharma. In particular, anti-programmed death-1 monoclonal antibodies(anti-PD-1) like Bristol Myers’ Nivolumab(BMS-936558), Merck’s Lambrolizumab (MK-3475), GSK’s AMP-224, Teva/CureTech’s CT-011 and Roche/Genentech’s […]

ASCO2013 Take Two: Battleground Hematology

As we said in our initial article on ASCO 2013[link], Gilead will have a significant presence at this year’s meeting. In the May 15th press program for ASCO, they will be featuring Idelalisib(GS-1101), Gilead’s delta-specific PI3K inhibitor. Novel oral agents with dramatic efficacy and limited toxicity have made the hematology space highly competitive. Abstracts can […]